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CHFR promotes metastasis of human gastric carcinoma by activating AKT and ERK via NRF2- ROS axis

Tumor suppressor gene CHFR (The Checkpoint with Forkhead-associated and Ring finger domains) is a mitotic checkpoint and frequently hypermethylated in gastric cancer. Our previous study found CHFR played a certain extent pro-tumor function in gastric cancer. However, little is known about the underl...

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Detalles Bibliográficos
Autores principales: He, Feiyun, Ye, Bin, Wu, Xiaomeng, Pan, Jundi, Wang, Jianbo, Wang, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080934/
https://www.ncbi.nlm.nih.gov/pubmed/37024798
http://dx.doi.org/10.1186/s12876-023-02724-4