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Using sensitivity analyses to understand bistable system behavior

BACKGROUND: Bistable systems, i.e., systems that exhibit two stable steady states, are of particular interest in biology. They can implement binary cellular decision making, e.g., in pathways for cellular differentiation and cell cycle regulation. The onset of cancer, prion diseases, and neurodegene...

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Detalles Bibliográficos
Autores principales: Sreedharan, Vandana, Bhalla, Upinder S., Ramakrishnan, Naren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080961/
https://www.ncbi.nlm.nih.gov/pubmed/37024783
http://dx.doi.org/10.1186/s12859-023-05206-2