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Using sensitivity analyses to understand bistable system behavior
BACKGROUND: Bistable systems, i.e., systems that exhibit two stable steady states, are of particular interest in biology. They can implement binary cellular decision making, e.g., in pathways for cellular differentiation and cell cycle regulation. The onset of cancer, prion diseases, and neurodegene...
Autores principales: | Sreedharan, Vandana, Bhalla, Upinder S., Ramakrishnan, Naren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080961/ https://www.ncbi.nlm.nih.gov/pubmed/37024783 http://dx.doi.org/10.1186/s12859-023-05206-2 |
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