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Spheroids derived from the stromal vascular fraction of adipose tissue self-organize in complex adipose organoids and secrete leptin

BACKGROUND: Adipose tissue-derived stromal vascular fraction (SVF) harbors multipotent cells with potential therapeutic relevance. We developed a method to form adipose spheroids (AS) from the SVF with complex organoid structure and enhanced leptin secretion upon insulin stimulation. METHODS: SVF wa...

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Detalles Bibliográficos
Autores principales: Robledo, Fermín, González-Hodar, Lila, Tapia, Pablo, Figueroa, Ana-María, Ezquer, Fernando, Cortés, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080976/
https://www.ncbi.nlm.nih.gov/pubmed/37024989
http://dx.doi.org/10.1186/s13287-023-03262-2