Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis

Osteoarthritis (OA), which carries an enormous disease burden across the world, is characterised by irreversible degeneration of articular cartilage (AC), and subsequently bone. The cellular cause of OA is unknown. Here, using lineage tracing in mice, we show that the BMP-antagonist Gremlin 1 (Grem1...

Descripción completa

Detalles Bibliográficos
Autores principales: Ng, Jia Q., Jafarov, Toghrul H., Little, Christopher B., Wang, Tongtong, Ali, Abdullah, Ma, Yan, Radford, Georgette A, Vrbanac, Laura, Ichinose, Mari, Whittle, Samuel, Hunter, David, Lannagan, Tamsin RM, Suzuki, Nobumi, Goyne, Jarrad M., Kobayashi, Hiroki, Wang, Timothy C., Haynes, David, Menicanin, Danijela, Gronthos, Stan, Worthley, Daniel L., Woods, Susan L., Mukherjee, Siddhartha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081168/
https://www.ncbi.nlm.nih.gov/pubmed/37034712
http://dx.doi.org/10.1101/2023.03.29.534651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081168/
https://www.ncbi.nlm.nih.gov/pubmed/37034712
http://dx.doi.org/10.1101/2023.03.29.534651

Ejemplares similares