Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis

BACKGROUND & AIMS: Epithelial disruption in eosinophilic esophagitis (EoE) encompasses both impaired differentiation and diminished barrier integrity. We have shown that lysyl oxidase (LOX), a collagen cross-linking enzyme, is upregulated in the esophageal epithelium in EoE. However, the functio...

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Detalles Bibliográficos
Autores principales: Sasaki, Masaru, Hara, Takeo, Wang, Joshua X., Zhou, Yusen, Kennedy, Kanak V., Umeweni, Nicole N., Alston, Maiya A., Spergel, Zachary C., Nakagawa, Ritsu, Mcmillan, Emily A., Whelan, Kelly A., Karakasheva, Tatiana A., Hamilton, Kathryn E., Ruffner, Melanie A., Muir, Amanda B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081173/
https://www.ncbi.nlm.nih.gov/pubmed/37034590
http://dx.doi.org/10.1101/2023.03.27.534387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081173/
https://www.ncbi.nlm.nih.gov/pubmed/37034590
http://dx.doi.org/10.1101/2023.03.27.534387

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