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Integrated single cell analysis shows chronic alcohol drinking disrupts monocyte differentiation in the bone marrow niche

Chronic alcohol drinking rewires circulating monocytes and tissue-resident macrophages towards heightened inflammatory states with compromised anti-microbial defenses. As these effects remain consistent in short-lived monocytes after a 1-month abstinence period it is unclear whether these changes ar...

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Detalles Bibliográficos
Autores principales: Lewis, Sloan A., Doratt, Brianna M, Qiao, Qi, Blanton, Madison B., Grant, Kathleen A., Messaoudi, Ilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081177/
https://www.ncbi.nlm.nih.gov/pubmed/37034734
http://dx.doi.org/10.1101/2023.03.29.534727