Massively Parallel Profiling of RNA-targeting CRISPR-Cas13d

Type VI CRISPR enzymes cleave target RNAs and are widely used for gene regulation, RNA tracking, and diagnostics. However, a systematic understanding of their RNA binding specificity and cleavage activation is lacking. Here, we describe RNA chip-hybridized association-mapping platform (RNA-CHAMP), a...

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Detalles Bibliográficos
Autores principales: Kuo, Hung-Che, Prupes, Joshua, Chou, Chia-Wei, Finkelstein, Ilya J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081190/
https://www.ncbi.nlm.nih.gov/pubmed/37034598
http://dx.doi.org/10.1101/2023.03.27.534188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081190/
https://www.ncbi.nlm.nih.gov/pubmed/37034598
http://dx.doi.org/10.1101/2023.03.27.534188

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