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Massively Parallel Profiling of RNA-targeting CRISPR-Cas13d
Type VI CRISPR enzymes cleave target RNAs and are widely used for gene regulation, RNA tracking, and diagnostics. However, a systematic understanding of their RNA binding specificity and cleavage activation is lacking. Here, we describe RNA chip-hybridized association-mapping platform (RNA-CHAMP), a...
Autores principales: | Kuo, Hung-Che, Prupes, Joshua, Chou, Chia-Wei, Finkelstein, Ilya J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081190/ https://www.ncbi.nlm.nih.gov/pubmed/37034598 http://dx.doi.org/10.1101/2023.03.27.534188 |
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