Cargando…

Basal forebrain activity predicts functional degeneration in the entorhinal cortex and decreases with Alzheimer’s Disease progression

BACKGROUND AND OBJECTIVES: Recent models of Alzheimer’s Disease (AD) suggest the nucleus basalis of Meynert (NbM) as the origin of structural degeneration followed by the entorhinal cortex (EC). However, the functional properties of NbM and EC regarding amyloid-β and hyperphosphorylated tau remain u...

Descripción completa

Detalles Bibliográficos
Autores principales: Mieling, Marthe, Göttlich, Martin, Yousuf, Mushfa, Bunzeck, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081194/
https://www.ncbi.nlm.nih.gov/pubmed/37034733
http://dx.doi.org/10.1101/2023.03.28.534523