Cargando…
APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1
HIV-1 must overcome multiple innate antiviral mechanisms to replicate in CD4(+) T lymphocytes and macrophages. Previous studies have demonstrated that the APOBEC3 (A3) family of proteins (at least A3D, A3F, A3G, and stable A3H haplotypes) contribute to HIV-1 restriction in CD4(+) T lymphocytes. Viru...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081227/ https://www.ncbi.nlm.nih.gov/pubmed/37034786 http://dx.doi.org/10.1101/2023.03.28.534666 |