Mechanism of histone H2B monoubiquitination by Bre1

Monoubiquitination of histone H2BK120/123 plays multiple roles in regulating transcription, DNA replication and the DNA damage response. The structure of a nucleosome in complex with the dimeric RING E3 ligase, Bre1, reveals that one RING domain binds to the nucleosome acidic patch, where it can pos...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Fan, Hicks, Chad W., Wolberger, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081246/
https://www.ncbi.nlm.nih.gov/pubmed/37034759
http://dx.doi.org/10.1101/2023.03.27.534461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081246/
https://www.ncbi.nlm.nih.gov/pubmed/37034759
http://dx.doi.org/10.1101/2023.03.27.534461

Ejemplares similares