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The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function
Polymeric (p) immunoglobulins (Igs) serve broad functions during vertebrate immune responses. Typically, pIgs contain between two and six Ig monomers, each with two antigen binding fragments and one fragment crystallization (Fc). In addition, many pIgs assemble with a joining-chain (JC); however, th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081254/ https://www.ncbi.nlm.nih.gov/pubmed/37034677 http://dx.doi.org/10.1101/2023.03.29.534771 |