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Sin3a Associated Protein 130kDa, sap130, plays an evolutionary conserved role in zebrafish heart development

Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle is reduced in size. A forward genetic screen in mice identified SIN3A associated protein 130kDa (Sap130), a protein in the chromatin modifying SIN3A/HDAC1 complex, as a gene contributing to the digenic etio...

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Detalles Bibliográficos
Autores principales: DeMoya, Ricardo A., Forman-Rubinsky, Rachel E., Fontaine, Deon, Shin, Joseph, Watkins, Simon C., Lo, Cecilia, Tsang, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081270/
https://www.ncbi.nlm.nih.gov/pubmed/37034673
http://dx.doi.org/10.1101/2023.03.30.534737