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Frustrated Microphase Separation Produces Interfacial Environment within Biological Condensates

The phase separation of intrinsically disordered proteins is emerging as an important mechanism for cellular organization. However, efforts to connect protein sequences to the physical properties of condensates, i.e., the molecular grammar, are hampered by a lack of effective approaches for probing...

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Detalles Bibliográficos
Autores principales: Latham, Andrew P., Zhu, Longchen, Sharon, Dina A., Ye, Songtao, Willard, Adam P., Zhang, Xin, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081284/
https://www.ncbi.nlm.nih.gov/pubmed/37034777
http://dx.doi.org/10.1101/2023.03.30.534967