Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities

Two distinct fates, pluripotent epiblast (EPI) and primitive (extra-embryonic) endoderm (PrE), arise from common progenitor cells, the inner cell mass (ICM), in mammalian embryos. To study how these sister identities are forged, we leveraged embryonic (ES) and eXtraembryonic ENdoderm (XEN) stem cell...

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Detalles Bibliográficos
Autores principales: Garg, Vidur, Yang, Yang, Nowotschin, Sonja, Setty, Manu, Kuo, Ying-Yi, Sharma, Roshan, Polyzos, Alexander, Salataj, Eralda, Murphy, Dylan, Jang, Amy, Pe’er, Dana, Apostolou, Effie, Hadjantonakis, Anna-Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081288/
https://www.ncbi.nlm.nih.gov/pubmed/37034770
http://dx.doi.org/10.1101/2023.03.28.534648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081288/
https://www.ncbi.nlm.nih.gov/pubmed/37034770
http://dx.doi.org/10.1101/2023.03.28.534648

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