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The small mycobacterial ribosomal protein, bS22, modulates aminoglycoside accessibility to its 16S rRNA helix-44 binding site

Treatment of tuberculosis continues to be challenging due to the widespread latent form of the disease and the emergence of antibiotic-resistant strains of the pathogen, Mycobacterium tuberculosis. Bacterial ribosomes are a common and effective target for antibiotics. Several second line anti-tuberc...

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Detalles Bibliográficos
Autores principales: Majumdar, Soneya, Deep, Ayush, Sharma, Manjuli R., Canestrari, Jill, Stone, Melissa, Smith, Carol, Koripella, Ravi K., Keshavan, Pooja, Banavali, Nilesh K., Wade, Joseph T., Gray, Todd A., Derbyshire, Keith M., Agrawal, Rajendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081302/
https://www.ncbi.nlm.nih.gov/pubmed/37034768
http://dx.doi.org/10.1101/2023.03.31.535098