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Preservation of co-expression defines the primary tissue fidelity of human neural organoids
Human neural organoid models offer an exciting opportunity for studying often inaccessible human-specific brain development; however, it remains unclear how precisely organoids recapitulate fetal/primary tissue biology. Here, we characterize field-wide replicability and biological fidelity through a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081321/ https://www.ncbi.nlm.nih.gov/pubmed/37034757 http://dx.doi.org/10.1101/2023.03.31.535112 |