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Preservation of co-expression defines the primary tissue fidelity of human neural organoids

Human neural organoid models offer an exciting opportunity for studying often inaccessible human-specific brain development; however, it remains unclear how precisely organoids recapitulate fetal/primary tissue biology. Here, we characterize field-wide replicability and biological fidelity through a...

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Detalles Bibliográficos
Autores principales: Werner, Jonathan M., Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081321/
https://www.ncbi.nlm.nih.gov/pubmed/37034757
http://dx.doi.org/10.1101/2023.03.31.535112