Lysosome transporter purification and reconstitution identifies Ypq1 pH-gated lysine transport and regulation

Lysosomes achieve their function through numerous transporters that import or export nutrients across their membrane. However, technical challenges in membrane protein overexpression, purification, and reconstitution hinder our understanding of lysosome transporter function. Here, we developed a pla...

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Detalles Bibliográficos
Autores principales: Arines, Felichi Mae, Wielenga, Aleksander, Burata, Olive E., Garcia, Francisco Narro, Stockbridge, Randy B., Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081341/
https://www.ncbi.nlm.nih.gov/pubmed/37034749
http://dx.doi.org/10.1101/2023.03.31.535002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081341/
https://www.ncbi.nlm.nih.gov/pubmed/37034749
http://dx.doi.org/10.1101/2023.03.31.535002

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