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Nucleolar structure connects with global nuclear organization

The nucleolus is a multi-functional nuclear body. To tease out the roles of nucleolar structure without resorting to multi-action drugs, we knocked down RNA polymerase I subunit RPA194 in HeLa cells by siRNA. Loss of RPA194 resulted in nucleolar structural segregation and effects on both nucleolus-p...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Ma, Hanhui, Baserga, Susan J., Pederson, Thoru, Huang, Sui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081344/
https://www.ncbi.nlm.nih.gov/pubmed/37034708
http://dx.doi.org/10.1101/2023.03.30.534966