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Nucleolar structure connects with global nuclear organization
The nucleolus is a multi-functional nuclear body. To tease out the roles of nucleolar structure without resorting to multi-action drugs, we knocked down RNA polymerase I subunit RPA194 in HeLa cells by siRNA. Loss of RPA194 resulted in nucleolar structural segregation and effects on both nucleolus-p...
Autores principales: | Wang, Chen, Ma, Hanhui, Baserga, Susan J., Pederson, Thoru, Huang, Sui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081344/ https://www.ncbi.nlm.nih.gov/pubmed/37034708 http://dx.doi.org/10.1101/2023.03.30.534966 |
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