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Cluster-Based Toxicity Estimation of Osteoradionecrosis via Unsupervised Machine Learning: Moving Beyond Single Dose-Parameter Normal Tissue Complication Probability by Using Whole Dose-Volume Histograms for Cohort Risk Stratification

PURPOSE: Given the limitations of extant models for normal tissue complication probability estimation for osteoradionecrosis (ORN) of the mandible, the purpose of this study was to enrich statistical inference by exploiting structural properties of data and provide a clinically reliable model for OR...

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Detalles Bibliográficos
Autores principales: Hosseinian, Seyedmohammadhossein, Hemmati, Mehdi, Dede, Cem, Salzillo, Travis C., van Dijk, Lisanne V., Mohamed, Abdallah S. R., Lai, Stephen Y., Schaefer, Andrew J., Fuller, Clifton D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081413/
https://www.ncbi.nlm.nih.gov/pubmed/37034700
http://dx.doi.org/10.1101/2023.03.24.23287710