Incorporating efficacy data from initial trials into subsequent evaluations: Application to vaccines against respiratory syncytial virus

BACKGROUND. When a randomized controlled trial fails to demonstrate statistically significant efficacy against the primary endpoint, a potentially costly new trial would need to be conducted to receive licensure. Incorporating data from previous trials might allow for the conduct of more efficient f...

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Detalles Bibliográficos
Autores principales: Warren, Joshua L., Sundaram, Maria, Pitzer, Virginia E., Omer, Saad B., Weinberger, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081417/
https://www.ncbi.nlm.nih.gov/pubmed/37034783
http://dx.doi.org/10.1101/2023.03.27.23287639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081417/
https://www.ncbi.nlm.nih.gov/pubmed/37034783
http://dx.doi.org/10.1101/2023.03.27.23287639

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