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Incorporating efficacy data from initial trials into subsequent evaluations: Application to vaccines against respiratory syncytial virus
BACKGROUND. When a randomized controlled trial fails to demonstrate statistically significant efficacy against the primary endpoint, a potentially costly new trial would need to be conducted to receive licensure. Incorporating data from previous trials might allow for the conduct of more efficient f...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081417/ https://www.ncbi.nlm.nih.gov/pubmed/37034783 http://dx.doi.org/10.1101/2023.03.27.23287639 |