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Development of a broadly active influenza intranasal vaccine adjuvanted with self-assembled particles composed of mastoparan-7 and CpG

Currently licensed vaccine adjuvants offer limited mucosal immunity, which is needed to better combat respiratory infections such as influenza. Mast cells (MCs) are emerging as a target for a new class of mucosal vaccine adjuvants. Here, we developed and characterized a nanoparticulate adjuvant comp...

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Detalles Bibliográficos
Autores principales: Ontiveros-Padilla, Luis, Batty, Cole J., Hendy, Dylan A., Pena, Erik S., Roque, John A., Stiepel, Rebeca T., Carlock, Michael A., Simpson, Sean R., Ross, Ted M., Abraham, Soman N., Staats, Herman F., Bachelder, Eric M., Ainslie, Kristy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081679/
https://www.ncbi.nlm.nih.gov/pubmed/37033992
http://dx.doi.org/10.3389/fimmu.2023.1103765