Reduction of DNA damage repair efficiency and accumulation of residual damage following chronic UVB-irradiation of HaCaT cells

Absorption of ultraviolet radiation (UVR) by DNA leads to the predominant formation of cyclobutane pyrimidine dimers (CPD). Since those CPD are responsible for the driver mutations found in skin cancers, their efficient repair is critical. We previously showed that pre-stimulation of fibroblasts wit...

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Detalles Bibliográficos
Autores principales: Dorr, Marie M., Rochette, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081739/
https://www.ncbi.nlm.nih.gov/pubmed/37027425
http://dx.doi.org/10.1371/journal.pone.0283572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081739/
https://www.ncbi.nlm.nih.gov/pubmed/37027425
http://dx.doi.org/10.1371/journal.pone.0283572

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