Adenovirus core protein V reinforces the capsid and enhances genome release from disrupted particles

Out of the three core proteins in human adenovirus, protein V is believed to connect the inner capsid surface to the outer genome layer. Here, we explored mechanical properties and in vitro disassembly of particles lacking protein V (Ad5-ΔV). Ad5-ΔV particles were softer and less brittle than the wi...

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Detalles Bibliográficos
Autores principales: Martín-González, Natalia, Gómez-González, Alfonso, Hernando-Pérez, Mercedes, Bauer, Michael, Greber, Urs F., San Martín, Carmen, de Pablo, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081844/
https://www.ncbi.nlm.nih.gov/pubmed/37027464
http://dx.doi.org/10.1126/sciadv.ade9910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081844/
https://www.ncbi.nlm.nih.gov/pubmed/37027464
http://dx.doi.org/10.1126/sciadv.ade9910

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