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Adenovirus core protein V reinforces the capsid and enhances genome release from disrupted particles
Out of the three core proteins in human adenovirus, protein V is believed to connect the inner capsid surface to the outer genome layer. Here, we explored mechanical properties and in vitro disassembly of particles lacking protein V (Ad5-ΔV). Ad5-ΔV particles were softer and less brittle than the wi...
Autores principales: | Martín-González, Natalia, Gómez-González, Alfonso, Hernando-Pérez, Mercedes, Bauer, Michael, Greber, Urs F., San Martín, Carmen, de Pablo, Pedro J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081844/ https://www.ncbi.nlm.nih.gov/pubmed/37027464 http://dx.doi.org/10.1126/sciadv.ade9910 |
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