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Widespread RNA hypoediting in schizophrenia and its relevance to mitochondrial function

RNA editing, the endogenous modification of nucleic acids, is known to be altered in genes with important neurological function in schizophrenia (SCZ). However, the global profile and molecular functions of disease-associated RNA editing remain unclear. Here, we analyzed RNA editing in postmortem br...

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Detalles Bibliográficos
Autores principales: Choudhury, Mudra, Fu, Ting, Amoah, Kofi, Jun, Hyun-Ik, Chan, Tracey W., Park, Sungwoo, Walker, David W., Bahn, Jae Hoon, Xiao, Xinshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081846/
https://www.ncbi.nlm.nih.gov/pubmed/37027465
http://dx.doi.org/10.1126/sciadv.ade9997