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The histone demethylase Kdm3 prevents auto-immune piRNAs production in Drosophila

Genome integrity of the animal germline is protected from transposable element activity by PIWI-interacting RNAs (piRNAs). While piRNA biogenesis is intensively explored, little is known about the genetical determination of piRNA clusters, the genomic sources of piRNAs. Using a bimodal epigenetic st...

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Detalles Bibliográficos
Autores principales: Casier, Karine, Autaa, Julie, Gueguen, Nathalie, Delmarre, Valérie, Marie, Pauline P., Ronsseray, Stéphane, Carré, Clément, Brasset, Emilie, Teysset, Laure, Boivin, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081847/
https://www.ncbi.nlm.nih.gov/pubmed/37027460
http://dx.doi.org/10.1126/sciadv.ade3872