Bombyx Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association

Bombyx Vasa (BmVasa) assembles non-membranous organelle, nuage or Vasa bodies, in germ cells, known as the center for Siwi-dependent transposon silencing and concomitant Ago3-piRISC biogenesis. However, details of the body assembly remain unclear. Here, we show that the N-terminal intrinsically diso...

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Detalles Bibliográficos
Autores principales: Yamazaki, Hiroya, Namba, Yurika, Kuriyama, Shogo, Nishida, Kazumichi M., Kajiya, Asako, Siomi, Mikiko C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081994/
https://www.ncbi.nlm.nih.gov/pubmed/37029111
http://dx.doi.org/10.1038/s41467-023-37634-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081994/
https://www.ncbi.nlm.nih.gov/pubmed/37029111
http://dx.doi.org/10.1038/s41467-023-37634-2

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