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Bombyx Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association
Bombyx Vasa (BmVasa) assembles non-membranous organelle, nuage or Vasa bodies, in germ cells, known as the center for Siwi-dependent transposon silencing and concomitant Ago3-piRISC biogenesis. However, details of the body assembly remain unclear. Here, we show that the N-terminal intrinsically diso...
Autores principales: | Yamazaki, Hiroya, Namba, Yurika, Kuriyama, Shogo, Nishida, Kazumichi M., Kajiya, Asako, Siomi, Mikiko C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081994/ https://www.ncbi.nlm.nih.gov/pubmed/37029111 http://dx.doi.org/10.1038/s41467-023-37634-2 |
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