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Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells

Iron overload is associated with various pathological changes which contribute to metabolic syndrome, many of which have been proposed to occur via damaging tissue through an excessive amount of reactive oxygen species (ROS) production. In this study, we established a model of iron overload in L6 sk...

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Detalles Bibliográficos
Autores principales: Sung, Hye Kyoung, Murugathasan, Mayoorey, Abdul-Sater, Ali A., Sweeney, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081999/
https://www.ncbi.nlm.nih.gov/pubmed/37029101
http://dx.doi.org/10.1038/s41419-022-05484-3