Cdc2-like kinases: structure, biological function, and therapeutic targets for diseases

The CLKs (Cdc2-like kinases) belong to the dual-specificity protein kinase family and play crucial roles in regulating transcript splicing via the phosphorylation of SR proteins (SRSF1–12), catalyzing spliceosome molecular machinery, and modulating the activities or expression of non-splicing protei...

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Detalles Bibliográficos
Autores principales: Song, Mengqiu, Pang, Luping, Zhang, Mengmeng, Qu, Yingzi, Laster, Kyle Vaughn, Dong, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082069/
https://www.ncbi.nlm.nih.gov/pubmed/37029108
http://dx.doi.org/10.1038/s41392-023-01409-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082069/
https://www.ncbi.nlm.nih.gov/pubmed/37029108
http://dx.doi.org/10.1038/s41392-023-01409-4

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