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Lysyl oxidase-like 2 processing by factor Xa modulates its activity and substrate preference

Lysyl oxidase-like 2 (LOXL2) has been identified as an essential mediator of extracellular matrix (ECM) remodeling in several disease processes including cardiovascular disease. Thus, there is growing interest in understanding the mechanisms by which LOXL2 is regulated in cells and tissue. While LOX...

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Detalles Bibliográficos
Autores principales: Wang, Huilei, Poe, Alan, Martinez Yus, Marta, Pak, Lydia, Nandakumar, Kavitha, Santhanam, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082071/
https://www.ncbi.nlm.nih.gov/pubmed/37029269
http://dx.doi.org/10.1038/s42003-023-04748-8