Could interventions on physical activity mitigate genomic liability for obesity? Applying the health disparity framework in genetically informed studies

Polygenic scores (PGS) are now commonly available in longitudinal cohort studies, leading to their integration into epidemiological research. In this work, our aim is to explore how polygenic scores can be used as exposures in causal inference-based methods, specifically mediation analyses. We propo...

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Detalles Bibliográficos
Autores principales: Herle, Moritz, Pickles, Andrew, Pain, Oliver, Viner, Russell, Pingault, Jean-Baptiste, De Stavola, Bianca L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Genetic Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082115/
https://www.ncbi.nlm.nih.gov/pubmed/36905531
http://dx.doi.org/10.1007/s10654-023-00980-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082115/
https://www.ncbi.nlm.nih.gov/pubmed/36905531
http://dx.doi.org/10.1007/s10654-023-00980-y

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