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Long-term response to pimitespib in postoperative recurrent gastrointestinal stromal tumors with PDGFRA D842V mutation: a case report

BACKGROUND: Exon 18 D842V, which is a point mutation from aspartic acid to valine at codon 842, is the most frequent mutation in Platelet-Derived Growth Factor Receptor alpha (PDGFRA)-mutated gastrointestinal stromal tumor (GIST). In the Japanese GIST guidelines, no standard systematic therapy is av...

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Detalles Bibliográficos
Autores principales: Teranishi, Ryugo, Takahashi, Tsuyoshi, Kurokawa, Yukinori, Saito, Takuro, Yamamoto, Kazuyoshi, Yamashita, Kotaro, Tanaka, Koji, Makino, Tomoki, Nakajima, Kiyokazu, Eguchi, Hidetoshi, Doki, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082137/
https://www.ncbi.nlm.nih.gov/pubmed/37027098
http://dx.doi.org/10.1186/s40792-023-01637-4