A high throughput bispecific antibody discovery pipeline

Bispecific antibodies (BsAbs) represent an emerging class of immunotherapy, but inefficiency in the current discovery has limited their broad clinical availability. Here we report a high throughput, agnostic, single-cell-based functional screening pipeline, comprising molecular and cell engineering...

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Detalles Bibliográficos
Autores principales: Segaliny, Aude I., Jayaraman, Jayapriya, Chen, Xiaoming, Chong, Jonathan, Luxon, Ryan, Fung, Audrey, Fu, Qiwei, Jiang, Xianzhi, Rivera, Rodrigo, Ma, Xiaoya, Ren, Ci, Zimak, Jan, Hedde, Per Niklas, Shang, Yonglei, Wu, George, Zhao, Weian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082157/
https://www.ncbi.nlm.nih.gov/pubmed/37029216
http://dx.doi.org/10.1038/s42003-023-04746-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082157/
https://www.ncbi.nlm.nih.gov/pubmed/37029216
http://dx.doi.org/10.1038/s42003-023-04746-w

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