Crystal structure of a highly conserved enteroviral 5′ cloverleaf RNA replication element

The extreme 5′-end of the enterovirus RNA genome contains a conserved cloverleaf-like domain that recruits 3CD and PCBP proteins required for initiating genome replication. Here, we report the crystal structure at 1.9 Å resolution of this domain from the CVB3 genome in complex with an antibody chape...

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Detalles Bibliográficos
Autores principales: Das, Naba K., Hollmann, Nele M., Vogt, Jeff, Sevdalis, Spiridon E., Banna, Hasan A., Ojha, Manju, Koirala, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082201/
https://www.ncbi.nlm.nih.gov/pubmed/37029118
http://dx.doi.org/10.1038/s41467-023-37658-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082201/
https://www.ncbi.nlm.nih.gov/pubmed/37029118
http://dx.doi.org/10.1038/s41467-023-37658-8

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