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Crystal structure of a highly conserved enteroviral 5′ cloverleaf RNA replication element
The extreme 5′-end of the enterovirus RNA genome contains a conserved cloverleaf-like domain that recruits 3CD and PCBP proteins required for initiating genome replication. Here, we report the crystal structure at 1.9 Å resolution of this domain from the CVB3 genome in complex with an antibody chape...
Autores principales: | Das, Naba K., Hollmann, Nele M., Vogt, Jeff, Sevdalis, Spiridon E., Banna, Hasan A., Ojha, Manju, Koirala, Deepak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082201/ https://www.ncbi.nlm.nih.gov/pubmed/37029118 http://dx.doi.org/10.1038/s41467-023-37658-8 |
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