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Prognostic value of O(6)-methylguanine-DNA methyltransferase hypermethylation and expression in head and neck cancer: A systematic review and meta-analysis

O(6)-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that maintains the stability of genetic information. MGMT is a strong prognostic biomarker in patients with glioblastoma. However, the effect of its gene hypermethylation and expression on the survival rate of head and neck cance...

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Detalles Bibliográficos
Autores principales: Yang, Huiwen, Zhou, Liuqing, Yang, Fan, Chen, Jingcai, Wang, Yanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082309/
https://www.ncbi.nlm.nih.gov/pubmed/37026932
http://dx.doi.org/10.1097/MD.0000000000033472