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The ATPase activity of the phosphatidylethanolamine flippase TAT-5 inhibits extracellular vesicle budding from the plasma membrane

Cells release extracellular vesicles (EVs) from their surface, but the mechanisms that govern EV release by plasma membrane budding are poorly understood. The lipid flippase TAT-5 inhibits EV release from the plasma membrane in C. elegans , but how the level of flippase activity regulates EV release...

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Detalles Bibliográficos
Autores principales: Pitts, Lauren R, Frondoni, Julia, Nguyen, Alexander T, Wehman, Ann M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082395/
https://www.ncbi.nlm.nih.gov/pubmed/37038482
http://dx.doi.org/10.17912/micropub.biology.000779