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Efficacy and Safety of Anakinra Plus Standard of Care for Patients With Severe COVID-19: A Randomized Phase 2/3 Clinical Trial

IMPORTANCE: COVID-19 pneumonia is often associated with hyperinflammation. The efficacy and safety of anakinra in treating patients with severe COVID-19 pneumonia and hyperinflammation are still unclear. OBJECTIVE: To assess the efficacy and safety of anakinra vs standard of care alone for patients...

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Detalles Bibliográficos
Autores principales: Fanlo, Patricia, Gracia-Tello, Borja del Carmelo, Fonseca Aizpuru, Eva, Álvarez-Troncoso, Jorge, Gonzalez, Andrés, Prieto-González, Sergio, Freire, Mayka, Argibay, Ana Belén, Pallarés, Lucio, Todolí, José Antonio, Pérez, Mercedes, Buján-Rivas, Segundo, Ibáñez, Berta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082404/
https://www.ncbi.nlm.nih.gov/pubmed/37027155
http://dx.doi.org/10.1001/jamanetworkopen.2023.7243