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Modeling of clinical phenotypes in systemic lupus erythematosus based on the platelet transcriptome and FCGR2a genotype

BACKGROUND: The clinical heterogeneity of SLE with its complex pathogenesis remains challenging as we strive to provide optimal management. The contribution of platelets to endovascular homeostasis, inflammation and immune regulation highlights their potential importance in SLE. Prior work from our...

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Detalles Bibliográficos
Autores principales: Cornwell, MacIntosh G., Bannoudi, Hanane El, Luttrell-Williams, Elliot, Engel, Alexis, Barrett, Tessa J., Myndzar, Khrystyna, Izmirly, Peter, Belmont, H. Michael, Clancy, Robert, Ruggles, Kelly V., Buyon, Jill P., Berger, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082503/
https://www.ncbi.nlm.nih.gov/pubmed/37029410
http://dx.doi.org/10.1186/s12967-023-04059-w