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Co-profiling reveals distinct patterns of genomic chromatin accessibility and gene expression in pulmonary hypertension caused by chronic hypoxia
INTRODUCTION: Aberrant gene expression is a key mechanism underlying pulmonary hypertension (PH) development. The alterations of genomic chromatin accessibility and their relationship with the aberrant gene expressions in PH are poorly understood. We used bulk Assay for Transposase-Accessible Chroma...
Autores principales: | Yu, Dongdong, Zhang, Ting, Zhou, Guangyuan, Wu, Zeang, Xiao, Rui, Zhang, Han, Liu, Bingxun, Li, Xiangpan, Ruiz, Matthieu, Dupuis, Jocelyn, Zhu, Liping, Hu, Qinghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082509/ https://www.ncbi.nlm.nih.gov/pubmed/37031175 http://dx.doi.org/10.1186/s12931-023-02389-3 |
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