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PKC-ζ mediated reduction of the extracellular vesicles-associated TGF-β1 overcomes radiotherapy resistance in breast cancer

BACKGROUND: Radiotherapy is widely applied in breast cancer treatment, while radiotherapy resistance is inevitable. TGF-β1 has been considered to be an endogenous factor for the development of radiotherapy resistance. As a large portion of TGF-β1 is secreted in an extracellular vesicles-associated f...

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Detalles Bibliográficos
Autores principales: Zhang, Fayun, Zheng, Zifeng, Wang, Luoyang, Zeng, Wenfeng, Wei, Wenjing, Zhang, Chunling, Zhao, Ziran, Liang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082517/
https://www.ncbi.nlm.nih.gov/pubmed/37029374
http://dx.doi.org/10.1186/s13058-023-01641-4