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Automatic block-wise genotype-phenotype association detection based on hidden Markov model

BACKGROUND: For detecting genotype-phenotype association from case–control single nucleotide polymorphism (SNP) data, one class of methods relies on testing each genomic variant site individually. However, this approach ignores the tendency for associated variant sites to be spatially clustered inst...

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Detalles Bibliográficos
Autores principales: Du, Jin, Wang, Chaojie, Wang, Lijun, Mao, Shanjun, Zhu, Bencong, Li, Zheng, Fan, Xiaodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082540/
https://www.ncbi.nlm.nih.gov/pubmed/37029361
http://dx.doi.org/10.1186/s12859-023-05265-5