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Automatic block-wise genotype-phenotype association detection based on hidden Markov model
BACKGROUND: For detecting genotype-phenotype association from case–control single nucleotide polymorphism (SNP) data, one class of methods relies on testing each genomic variant site individually. However, this approach ignores the tendency for associated variant sites to be spatially clustered inst...
Autores principales: | Du, Jin, Wang, Chaojie, Wang, Lijun, Mao, Shanjun, Zhu, Bencong, Li, Zheng, Fan, Xiaodan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082540/ https://www.ncbi.nlm.nih.gov/pubmed/37029361 http://dx.doi.org/10.1186/s12859-023-05265-5 |
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