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Anti‐β7 integrin treatment impedes the recruitment on non‐classical monocytes to the gut and delays macrophage‐mediated intestinal wound healing

BACKGROUND: Closing mucosal defects to reach mucosal healing is an important goal of therapy in inflammatory bowel disease (IBD). Among other cells, monocyte‐derived macrophages are centrally involved in such intestinal wound healing. We had previously demonstrated that the anti‐α4β7 integrin antibo...

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Detalles Bibliográficos
Autores principales: Sommer, Katrin, Heidbreder, Karin, Kreiss, Lucas, Dedden, Mark, Paap, Eva‐Maria, Wiendl, Maximilian, Becker, Emily, Atreya, Raja, Müller, Tanja M., Atreya, Imke, Waldner, Maximilian, Schürmann, Sebastian, Friedrich, Oliver, Neurath, Markus F., Zundler, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082567/
https://www.ncbi.nlm.nih.gov/pubmed/37029786
http://dx.doi.org/10.1002/ctm2.1233