Predicting compound activity from phenotypic profiles and chemical structures

Predicting assay results for compounds virtually using chemical structures and phenotypic profiles has the potential to reduce the time and resources of screens for drug discovery. Here, we evaluate the relative strength of three high-throughput data sources—chemical structures, imaging (Cell Painti...

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Detalles Bibliográficos
Autores principales: Moshkov, Nikita, Becker, Tim, Yang, Kevin, Horvath, Peter, Dancik, Vlado, Wagner, Bridget K., Clemons, Paul A., Singh, Shantanu, Carpenter, Anne E., Caicedo, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082762/
https://www.ncbi.nlm.nih.gov/pubmed/37031208
http://dx.doi.org/10.1038/s41467-023-37570-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082762/
https://www.ncbi.nlm.nih.gov/pubmed/37031208
http://dx.doi.org/10.1038/s41467-023-37570-1

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